Curing with Sound

Ep3: Nir Lipsman, MD, PhD | Pioneering Focused Ultrasound Applications for the Brain

In this episode of Curing with Sound, Dr. Neal Kassell, founder and chairman of the Focused Ultrasound Foundation, is joined by Dr. Nir Lipsman, a neurosurgeon and senior scientist at Sunnybrook Research Institute in Toronto, Canada. Dr. Kassell considers Dr. Lipsman to be one of the most influential clinicians in the development and adoption of focused ultrasound, having pioneered several world-first clinical trials for various brain disorders.

Throughout the conversation, Dr. Lipsman discusses the evolution of his focused ultrasound program at Sunnybrook, which has grown exponentially over the past decade. His team has treated over 500 patients across a wide range of indications, including essential tremor, Parkinson's disease, obsessive-compulsive disorder, major depression, and various types of brain tumors.

One of the most exciting aspects of Dr. Lipsman's work is the use of focused ultrasound for opening the blood-brain barrier to enhance drug delivery. He shares the groundbreaking results of a trial in which they were able to visually confirm the passage of a large molecule, trastuzumab, directly into the brain to target metastatic breast cancer tumors. This achievement holds immense promise for the treatment of numerous brain disorders, particularly in the neurodegenerative space, where focused ultrasound could potentially change the natural history of diseases like Parkinson's and Alzheimer's.

Dr. Lipsman emphasizes the importance of collaboration and parallel progress in advancing the field of focused ultrasound. He highlights the critical role of the Focused Ultrasound Foundation in supporting and fostering the growth of his program and the global focused ultrasound community.

Looking to the future, Dr. Lipsman envisions focused ultrasound becoming a routine, well-tolerated outpatient procedure that can not only treat but also prevent and diagnose brain disorders. He remains committed to building a strong, multidisciplinary team at Sunnybrook and working with the global community to bring the transformative potential of focused ultrasound to patients worldwide. Harquail Centre for Neuromodulation 

Show Transcript----------------------------QUESTIONS?Email podcast@fusfoundation.org if you have a question or comment about the show, or if you would you like to connect about future guest appearances. 
Email info@fusfoundation.org if you have questions about focused ultrasound or the Foundation. 
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Ep2: Ken Dychtwald, PhD & Katsuto Shinohara, MD | Navigating a Prostate Cancer Diagnosis with Focused Ultrasound

In this episode of Curing with Sound, we speak with Dr. Ken Dychtwald, renowned gerontologist, best-selling author, and Founder of Age Wave, and Dr. Katsuto Shinohara, a leading urologic oncologist at UCSF. 
Dr. Dychtwald, who has dedicated his life to studying gerontology and the aging population, shares his initial shock upon being diagnosed with prostate cancer. He emphasizes the importance of men openly discussing prostate health issues, as many of his friends had experienced similar diagnoses.
When presented with treatment options, Dr. Dychtwald was intrigued by the potential of high-intensity focused ultrasound (HIFU), a minimally invasive procedure he had previously advocated for in his work. Under the care of Dr. Shinohara at UCSF, Dr. Dychtwald underwent HIFU treatment, which precisely targets cancerous tissue while preserving surrounding healthy tissue.
The procedure itself was swift, lasting less than 15 minutes, and Dr. Dychtwald was able to return to work the same day. He expresses his gratitude for the availability of this advanced technology and encourages others to inquire about focused ultrasound as a potential treatment option.
Both Dr. Dychtwald and Dr. Shinohara express optimism about the advancements in medical technology and the potential for focused ultrasound to revolutionize the treatment of various cancers and other conditions, ultimately contributing to improved quality of life and longevity.
Show Transcript----------------------------QUESTIONS?Email podcast@fusfoundation.org if you have a question or comment about the show, or if you would you like to connect about future guest appearances. 
Email info@fusfoundation.org if you have questions about focused ultrasound or the Foundation. 
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Ep1: Neal Kassell, MD | A Remarkable Journey from Unconventional Student to World-Renowned Neurosurgeon

In the premiere episode of "Curing with Sound," we spotlight Dr. Neal Kassell, the Founder and Chairman of the Focused Ultrasound Foundation. Despite being blind in one eye and not completing his undergraduate degree, Dr. Kassell's unwavering commitment to making a significant impact on the world propelled him to become a leading neurosurgeon and a pioneer for focused ultrasound therapy.From a young age, Dr. Kassell was drawn to neurosurgery, gaining experience in a research lab at the age of 16 and later performing life-saving surgeries that would impact the lives of prominent figures and everyday individuals alike. His quest for better treatment options led him to focused ultrasound, a revolutionary noninvasive technology with the potential to transform treatment for a wide range of medical disorders, from neurodegenerative diseases like Alzheimer’s and Parkinson’s to cancer.Dr. Kassell is now spearheading the global adoption of this cutting-edge therapy through the Focused Ultrasound Foundation, which he established in 2006, with the mission of redefining patient care and improving millions of lives worldwide. His dedication to advancing medical innovation is not just about a breakthrough technology; it's about the power of determination and the passion to help others, even in the face of personal challenges.Tune in to hear Dr. Kassell’s inspiring story, learn about the future of medical treatment with focused ultrasound, and discover how his vision is bringing hope and healing to countless individuals around the world.----------------------------QUESTIONS?Email podcast@fusfoundation.org if you have a question or comment about the show, or if you would you like to connect about future guest appearances. 
Email info@fusfoundation.org if you have questions about focused ultrasound or the Foundation. 
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Ep0: Introduction to Curing with Sound

Welcome to Curing with Sound, a podcast presented by the Focused Ultrasound Foundation. In each episode, we'll explore the revolutionary therapy of focused ultrasound and how it's transforming the treatment of serious diseases and medical conditions such as Alzheimer's, Parkinson's, cancer, and more.Join host Allison Preston-Smith as she engages in thought-provoking discussions with leading researchers, medical experts, influential advocates, and the patients who have experienced the life-changing benefits of focused ultrasound firsthand.We'll also highlight the Foundation's steadfast commitment to advancing this technology and making it accessible to patients worldwide. You'll learn the latest advancements, clinical trials, and success stories, and gain a deeper understanding of how focused ultrasound works, its current applications, and its potential to alter the future of healthcare.Whether you're a doctor seeking cutting-edge treatment options, someone facing a health challenge, or simply fascinated with the future of science and medicine, Curing with Sound is your gateway to the extraordinary world of focused ultrasound and how its poised to reshape the medical landscape.
----------------------------QUESTIONS?Email podcast@fusfoundation.org if you have a question or comment about the show, or if you would you like to connect about future guest appearances. 
Email info@fusfoundation.org if you have questions about focused ultrasound or the Foundation. 
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